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Pathology, natural history and treatment of abdominal aortic aneurysms

机译:腹主动脉瘤的病理,自然病史和治疗

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摘要

With increasing age of the population and improvement of diagnostic tools, the incidence of abdominal aortic aneurysms (AAA) has been rising steadily. Despite an improvement in operative and interventional treatment options, AAA is the cause of death in 1–3% of men over 65 years of age in industrial countries, mostly due to rupture [1]. Therefore, routine screening for AAA by ultrasonography has been postulated in the past: a 60 year old man with an abdominal aortic diameter of less than 3 cm has a life-time risk of developing AAA close to zero. However, routine screening has not been found to be cost effective. Despite of the results of two well-designed studies, the limits of AAA qualifying the patient for surgery or intervention in contrast to conservative treatment is still a matter of debate. The present review article summarizes the current knowledge of the pathology, incidence, risks, natural course as well as symptoms and current treatment strategies of AAA on the basis of the recent literature.
机译:随着人口年龄的增长和诊断工具的改进,腹主动脉瘤(AAA)的发病率一直在稳步上升。尽管手术和介入治疗选择有所改善,但在工业化国家中,AAA是导致65%以上年龄段的1-3%男性死亡的原因[1]。因此,过去已经提出了通过超声检查对AAA进行常规筛查的方法:一名60岁的腹主动脉直径小于3 cm的男子终生罹患AAA的风险接近零。但是,常规筛查尚未发现具有成本效益。尽管有两项精心设计的研究的结果,但相对于保守治疗而言,AAA能否使患者有资格接受手术或干预仍是一个有争议的问题。本综述文章根据最近的文献总结了AAA的病理学,发病率,风险,自然病程以及症状和目前的治疗策略。

著录项

  • 来源
    《Clinical Research in Cardiology》 |2007年第3期|140-151|共12页
  • 作者单位

    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany;

    Department of Vascular Surgery, Ruprechts-Karls University Heidelberg, Im Neuenheimer Feld 410 and 110, 69120 Heidelberg, Germany;

    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany;

    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany;

    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany;

    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Aneurysm; aorta; rupture; surgery; endovascular treatment;

    机译:动脉瘤;主动脉;破裂;手术;血管内治疗;

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