Microfluidic systems on a printed wiring board platform

摘要

Purpose - The purpose of this paper is to present the development of printed wiring board (PWB)-based microfluidic building blocks and theirrnintegration into systems for DNA amplification and electronic detection.rnDesign/methodology/approach - Technologies from embedded passives (EP) and photolithographic high-density interconnect are integrated into arntraditional PWB platform to enable multifunctional electrochemical sensors for on-chip detection of biological assays.rnFindings - PWB materials and processes can be applied to develop microelectromechanical systems (MEMS) and microfluidic systems. On-chip heatersrnusing EP have been demonstrated with excellent accuracy. The on-chip heaters can be used for localized temperature control as well as heat air pumps.rnThe integration of EP and microchannels is a promising approach to add functionalities to the PWB-based microsystems.rnResearch limitations/implications - Further integration of microchannels with the embedded heaters and electrochemical sensors will increase therncompactness, functionality, and value of the PWB-based microfluidic systems.rnOriginality/value - The paper describes the development and integration of PWB-based building-blocks such as EP and microchannels for MEMS andrnmicrofluidic applications. These elements will enable new applications and enhanced functionalities of PWB.