Research on nucleolar regions of hippocampal neuron in Alzheimer's disease

摘要

Conclusion Nissl's stain demonstrates the hy- pofunction of the hippocampal neurons in the elderly ant he AD patients. The Silver stain of NORs shows the declined of rDNA transcription activity of the nucleoli of the hippocampal neurons in the elderly and the AD patients. However, the transcription activity of the nu- cleoli of the hippocampal neurons of AD patients was relatively improved, and the cellular genetic expression of the cell's population was relatively strengthened. These cellular morphological changes have probably Reflected he cellular defensive system.