In(OTf)<sub>3</sub>-Catalyzed Synthesis of Functionalized 1,5-Benzodiazepines from o-Phenylenediamine and Alkyl Propiolates under Solvent-Free Reaction Conditions

Haisheng Wu; Jin Yang; Lei Wang

首页> 外文期刊>Chinese Journal of Chemistry >In(OTf)₃-Catalyzed Synthesis of Functionalized 1,5-Benzodiazepines from o-Phenylenediamine and Alkyl Propiolates under Solvent-Free Reaction Conditions

【24h】

In(OTf)₃-Catalyzed Synthesis of Functionalized 1,5-Benzodiazepines from o-Phenylenediamine and Alkyl Propiolates under Solvent-Free Reaction Conditions

机译：In（OTf）_{3 催化在无溶剂反应条件下由邻苯二胺和丙炔酸烷基酯合成功能化的1,5-苯二氮卓}

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

A simple, environmental-friendly, and practical method for the synthesis of benzodiazepine derivatives through a reaction of substituted o-phenylenediamines with alkyl propiolates has been developed. The reactions generated the 1,5-benzodiazepines in good to excellent yields in the presence of catalytic amount of In(OTf)₃ under solvent-free reaction conditions.

机译：已经开发了一种简单，环境友好，实用的方法，该方法通过取代的邻苯二胺与丙酸烷基酯的反应合成苯并二氮杂卓衍生物。在无溶剂反应条件下，在催化量的In（OTf）_{3 存在下，反应生成的1,5-苯并二氮杂in具有良好的收率。}

著录项

来源
《Chinese Journal of Chemistry》 |2011年第8期|1721-1726|共6页
作者
Haisheng Wu; Jin Yang; Lei Wang;
展开▼
作者单位

Department of Chemistry Huaibei Normal University Huaibei Anhui 235000 China;

State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai 200032 China;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词
benzodiazepines; o-phenylenediamines; alkyl propiolates; In(OTf)sub3/sub; solvent-free;

机译：苯二氮卓;邻苯二胺;丙酸烷基酯;In（OTf）sub 3 / sub;无溶剂;

相似文献

外文文献
中文文献
专利

1. In（OTf）3-Catalyzed Synthesis of Functionalized 1,5-Benzodiazepines from o-Phenylenediamine and Alkyl Propiolates under Solvent-Free Reaction Conditions [J] . 吴海生, 杨进, 王磊中国化学（英文版） . 2011,第008期

机译：在无溶剂条件下，由邻苯二胺和丙酸烷基酯在（OTf）3-催化下合成功能化的1,5-苯二氮卓
2. In（OTf）3-Catalyzed Synthesis of Functionalized 1,5-Benzodiazepines from o-Phenylenediamine and Alkyl Propiolates under Solvent-Free Reaction Conditions [J] . 吴海生, 杨进, 王磊中国化学：英文版 . 2011,第008期

机译：在无溶剂条件下，由邻苯二胺和丙酸烷基酯在（OTf）3-催化下合成功能化的1,5-苯二氮卓
3. An Efficient Synthesis of 1,5-Benzodiazepine Derivatives by Lanthanide Trichloride-catalyzed Condensation of o-Phenylenediamine with ,-Unsaturated Ketone under Mild Conditions [J] . Shan-E FENG, Fan XU, Qi SHEN Chinese Journal of Chemistry . 2008,第7期

机译：轻度条件下镧系三氯化物催化邻苯二胺与-不饱和酮的缩合反应可高效合成1,5-苯并二氮杂卓衍生物
4. One-pot Synthesis of Anthraquinones by Sc(OTf)3-catalyzed Tandem Reaction [C] . Yohei Toriyama, Yoko Yasuno, Tetsuro Shinada 日本化学会春季年会講演予稿集 . 2018

机译：SC（OTF）3催化串联反应的蒽醌合成蒽醌
5. I. Tertiary aryl sulfonamides as new cross coupling partners for nickel catalyzed Kumada-Corriu-Tamao reductive and carbon-carbon bond forming cross coupling reactions. II. N-sulfonyl deprotection under mild nickel(0) catalyzed Kumada-Corriu-Tamao coupling conditions and development of the N-Ans protecting group. III. Synthesis and application of 3,3'-di-(2-pyridyl)-1,1'-bi-2-naphthol ligands [D] . Milburn, Robert Ronald 2004

机译：I.叔芳基磺酰胺作为镍催化的Kumada-Corriu-Tamao还原和碳-碳键形成交叉偶联反应的新交叉偶联伴侣。二。在温和的镍（0）下N-磺酰基脱保护催化了Kumada-Corriu-Tamao偶联条件和N-Ans保护基的发展。三， 3,3'-二-（2-吡啶基）-1,1'-bi-2-萘酚配体的合成及应用
6. Highly Efficient Synthesis of Substituted 34-Dihydropyrimidin-2-(1H)-ones (DHPMs) Catalyzed by Hf(OTf)4: Mechanistic Insights into Reaction Pathways under Metal Lewis Acid Catalysis and Solvent-Free Conditions [O] . Rui Kong, Shuai-Bo Han, Jing-Ying Wei, 2019

机译：Hf（OTf）4催化的高效取代34-二氢嘧啶-2-（1H）-ones（DHPMs）合成：金属路易斯酸催化和无溶剂条件下反应途径的机理研究
7. Highly Efficient Synthesis of Substituted 3,4-Dihydropyrimidin-2-(1H)-ones (DHPMs) Catalyzed by Hf(OTf)4: Mechanistic Insights into Reaction Pathways under Metal Lewis Acid Catalysis and Solvent-Free Conditions [O] . Rui Kong, Shuai-Bo Han, Jing-Ying Wei, 2019

机译：高效合成由HF（OTF）4催化的取代的3,4-二氢嘧啶-2-（1H）-ONE（DHPMS）（DHPMS）4：金属路易斯酸催化下的反应途径和无溶剂条件下的机械洞察力

In(OTf)3-Catalyzed Synthesis of Functionalized 1,5-Benzodiazepines from o-Phenylenediamine and Alkyl Propiolates under Solvent-Free Reaction Conditions

摘要

著录项

相似文献

相关主题

期刊订阅

In(OTf)₃-Catalyzed Synthesis of Functionalized 1,5-Benzodiazepines from o-Phenylenediamine and Alkyl Propiolates under Solvent-Free Reaction Conditions