Brain tissue oxygen tension monitoring in pediatric severe traumatic brain injury Part 2: Relationship with clinical, physiological, and treatment factors

摘要

Introduction Brain tissue oxygen tension (PbtO₂) monitoring is used increasingly in adult severe traumatic brain injury (TBI) management. Several factors are known to influence PbtO₂ in adults, but the variables that affect PbtO₂ in pediatric TBI are not well described. This study examines the relationships between PbtO₂ and (1) physiological markers of potential secondary insults commonly used in pediatric TBI, in particular intracranial pressure (ICP), cerebral perfusion pressure (CPP), and systemic hypoxia, and (2) other clinical factors and treatment received that may influence PbtO₂.