Magnetic, Luminescent Eu-Doped Mg–Al Layered Double Hydroxide and Its Intercalation for Ibuprofen

摘要

A magnetic, luminescent Eu-doped Mg–Al layered double hydroxide with ibuprofen (IBU) intercalated in the gallery has been successfully prepared by a simple coprecipitation method. The physicochemical properties of the samples were well characterized by powder XRD, TEM, FTIR, TGA, inductively coupled plasma MS (ICP-MS), vibrating sample magnetometry (VSM), and fluorospectrophotometry. The results revealed that Fe₃O₄ nanoparticles are coated on the surface of layered double hydroxides and the obtained (Mg2Al_0.95Eu_0.05)_Fe–(IBU) sample exhibits both superparamagnetic and luminescent properties, with a saturation magnetization value of 1.86 emu g−1 and a strong emission band at 610 nm, respectively. Additionally, it was found that the ibuprofen loading amount is about 31 % (w/w), and the intercalated ibuprofen possesses sustained release behavior when the magnetic, luminescent composite is immersed in simulated body fluid (SBF).