Enantioselective Reduction of Ketones and Imines Catalyzed by (CN-Box)ReV–Oxo Complexes†

摘要

The development and application of chiral, non-racemic ReV–oxo complexes to the enantioselective reduction of prochiral ketones is described. In addition to the enantioselective reduction of prochiral ketones, we report the application of these complexes to 1) a tandem Meyer–Schuster rearrangement/reduction to access enantioenriched allylic alcohols and 2) the enantioselective reduction of imines.