Safe, facile radical-based reduction and hydrosilylation reactions in a microreactor using tris(trimethylsilyl)silane

摘要

A highly efficient system for tris(trimethylsilyl)silane (TTMSS) mediated deoxygenation, dehalogenation and hydrosilylation reactions is described in a microstructured device; this convenient platform enables the scale up of radical-based processes.rnMicrostructured continuous-flow reactors and chip based microreactors are becoming increasingly popular to overcome hurdles associated with the use of batch reactors in synthetic chemistry. Traditional batch methods have inherent limitations regarding the optimisation of reaction conditions and scale-up.