A facile in situ generation of dithiocarbamate ligands for stable gold nanoparticle-oligonucleotide conjugates

摘要

Here we demonstrate a facile strategy of preparing gold nano-particle (AuNP) and DNA conjugates by in situ generation of strong metal affinity capping ligands, dithiocarbamates (DTC) modified oligonucleotides; the conjugates produced are stable at elevate