A Natural Carbohydrate Substrate For Mycobacterium Tuberculosis Methionine Sulfoxide Reductase A

摘要

Enzymatic reduction of the methylsulfinylxylofuranosyl (MSX) groups in lipoarabinomannan provides proof of the absolute configuration of MSX and a possible biochemical mechanism for oxidative protection in Mycobacterium tuberculosis.rnTuberculosis (TB) remains a major threat to world health, with 9.2 million new cases and 1.7 million deaths from TB in 2006.