Palladium-catalyzed decarboxylative 1,2-addition of carboxylic acids to aldehydes or imines

摘要

The first example of palladium-catalyzed decarboxylative 1,2-addition of carboxylic acids to aldehydes or imines under mild conditions is described.rnSince Miyaura and co-workers reported the rhodium-catalyzed 1,2-addition in 1998, using transition metal complexes of rhodium, palladium, nickel, copper and platinum as catalysts for 1,2-addition reactions of organoboronic acids to aldehydes or imines has become established as a universal tool for C-C bond formation.