Rhodium-mediated activation of an alkane-type C-H bond

摘要

Abnormal C4-bonding of N-heterocyclic carbenes effectively modulates the electron density at rhodium and allows for the selective cleavage of an unactivated C(sp~3)-H bond, whereas no such intramolecular C-H bond breaking is observed when the carbene binds normally through the C2 carbon.