A simple strategy for charge selective biopolymer sensing

摘要

Polysaccharide-induced protein fluorescence 'turn-on' responses have been studied in the presence of similarly charged micelle at pH ～3. Quenched protein fluorescence is selectively recovered ('on' state) for bovine serum albumin (BSA) with sodium carboxy methyl cellulose (SCMC) and for pepsin (PS) with chitosan (CS) with starting ultra low concentrations of 0.04 uM and 0.008 uM respectively. Development of fluorescence chemosensors for sensing bio-analytes is a highly demanding area in present day chemistry and biology.