Lithium cation enhances anion binding in a tripodal phosphine oxide-based ditopic receptor

摘要

A tripodal ditopic receptor presents H-bond donors and a phosphine oxide to potential guests. In the idealized binding conformation, an endohedral P=O functionality provides enhanced halide binding in the presence of lithium with the greatest △△G° observed for bromide, while minimal changes in A,, are observed in the presence of sodium.