Selective syntheses of no-carrier-added 2- and 3-[~(18)F]fluorohalopyridines through the radiofluorination of halopyridinyl(4'-methoxy phenyl)iodonium tosylates

Joong-Hyun Chun; Victor W. Pike

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Selective syntheses of no-carrier-added 2- and 3-[~(18)F]fluorohalopyridines through the radiofluorination of halopyridinyl(4'-methoxy phenyl)iodonium tosylates

机译：通过卤代吡啶基（4'-甲氧基苯基）碘代甲苯磺酸盐的放射性氟化选择性合成无载体的2-和3- [〜（（18）F]氟卤代吡啶

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摘要

No-carrier-added 2- and 3-[~(18)F]fluorohalopyridines were readily synthesized as potentially useful labeling synthons for prospective PET radiotracers through the selective radiofluorination of halopyridinyl(4'-methoxyphenyl)iodonium tosylates, themselves conveniently prepared in a single pot from iodohalopyridines.

机译：通过卤代吡啶基（4'-甲氧基苯基）碘代甲苯磺酸盐的选择性放射性氟化，可以方便地合成无载体的2-和3- [〜（18）F]氟卤代吡啶，它们可能对潜在的PET放射性示踪剂有用。从碘卤吡啶中取出一锅。

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《Chemical Communications》 |2012年第79期|p.9921-9923|共3页
作者
Joong-Hyun Chun; Victor W. Pike;
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Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3 C346A, 10 Center Drive, Bethesda, MD 20892-1003, USA;

Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3 C346A, 10 Center Drive, Bethesda, MD 20892-1003, USA;

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6. Selective syntheses of no-carrier-added 2- and 3-18Ffluorohalopyridines through the radiofluorination of halopyridinyl(4′-methoxyphenyl)iodonium tosylates [O] . Joong-Hyun Chun, Victor W. Pike -1

机译：的选择性合成没有添加载体的2-和3- 18 F通过卤代吡啶（4-甲氧基苯基）的放射性氟化fluorohalopyridines碘鎓甲苯磺酸酯
7. Selective syntheses of no-carrier-added 2- and 3-18Ffluorohalopyridines through the radiofluorination of halopyridinyl(4′-methoxyphenyl)iodonium tosylates [O] . Joong-Hyun Chun, Victor W. Pike 2012

机译：通过卤代吡啶基（4'-甲氧基苯基）碘化硅烷酯的酰基氟化氢化物的无载体添加的2-和3-18F氟ohalopyIne的选择性合成

Selective syntheses of no-carrier-added 2- and 3-[~(18)F]fluorohalopyridines through the radiofluorination of halopyridinyl(4'-methoxy phenyl)iodonium tosylates

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