首页> 外文期刊>Chemical Communications >Hybridization-triggered isothermal signal amplification coupled with MutS for label-free and sensitive fluorescent assay of SNPs
【24h】

Hybridization-triggered isothermal signal amplification coupled with MutS for label-free and sensitive fluorescent assay of SNPs

机译:杂交触发的等温信号放大与MutS结合使用,可对SNP进行无标记的灵敏荧光测定

获取原文
获取原文并翻译 | 示例
       

摘要

Combining the specific recognization of MutS protein for mismatched DNA sequences with the target-driven molecular switch that acts as both the template and primer of the polymerization reaction, a new label-free and sensitive fluorescent assay strategy for specific single-stranded DNA sequences or SNPs is proposed.
机译:将针对错配的DNA序列的MutS蛋白的特异性识别与充当聚合反应的模板和引物的靶点驱动的分子开关相结合,为特定的单链DNA序列或SNP提供了一种新的无标记灵敏的荧光检测策略被提议。

著录项

  • 来源
    《Chemical Communications》 |2012年第45期|p.5659-5661|共3页
  • 作者单位

    State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, and College of Materials and Engineering, Hunan University, Changsha, 410082, P. R. China;

    State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, and College of Materials and Engineering, Hunan University, Changsha, 410082, P. R. China,Center for Research at the Bio/Nano Interface, Department of Chemistry and Department of Physiology and Functional Genomics, Shands Cancer Center and UF Genetics Institute, University of Florida, Gainesville, Florida, 32611-7200, USA;

    State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, and College of Materials and Engineering, Hunan University, Changsha, 410082, P. R. China;

    Center for Research at the Bio/Nano Interface, Department of Chemistry and Department of Physiology and Functional Genomics, Shands Cancer Center and UF Genetics Institute, University of Florida, Gainesville, Florida, 32611-7200, USA;

    State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, and College of Materials and Engineering, Hunan University, Changsha, 410082, P. R. China;

    State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, and College of Materials and Engineering, Hunan University, Changsha, 410082, P. R. China;

    State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, and College of Materials and Engineering, Hunan University, Changsha, 410082, P. R. China;

    State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, and College of Materials and Engineering, Hunan University, Changsha, 410082, P. R. China,Center for Research at the Bio/Nano Interface, Department of Chemistry and Department of Physiology and Functional Genomics, Shands Cancer Center and UF Genetics Institute, University of Florida, Gainesville, Florida, 32611-7200, USA;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

  • 入库时间 2022-08-17 13:20:44

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号