Synthesis of novel lidocaine-releasing poly(diol-co-citrate) elastomers by using deep eutectic solvents

M. Conception Serrano; Maria C. Gutierrez; Ricardo Jimenez; M. Luisa Ferrer; Francisco del Monte

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Synthesis of novel lidocaine-releasing poly(diol-co-citrate) elastomers by using deep eutectic solvents

机译：用深共熔溶剂合成新型利多卡因释放性聚（柠檬酸二醇共聚物）弹性体

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Poly(octanediol-co-citrate) elastomers containing high loading of lidocaine were synthesized at temperatures below 100 ℃ by means of using deep eutectic mixtures of 1,8-octanediol and lidocaine. The preservation of lidocaine integrity resulted in high-capacity drug-eluting elastomers.

机译：通过使用1,8-辛二醇和利多卡因的深共晶混合物，在低于100℃的温度下合成了含有高负荷利多卡因的聚（辛二醇-柠檬酸酯）弹性体。利多卡因完整性的保留导致了高容量药物洗脱弹性体。

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《Chemical Communications》 |2012年第4期|p.579-581|共3页
作者
M. Conception Serrano; Maria C. Gutierrez; Ricardo Jimenez; M. Luisa Ferrer; Francisco del Monte;
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Institute de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigations Cientificas (CSIC), Cantoblanco 28049,Madrid, Spain;

Institute de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigations Cientificas (CSIC), Cantoblanco 28049,Madrid, Spain;

Institute de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigations Cientificas (CSIC), Cantoblanco 28049,Madrid, Spain;

Institute de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigations Cientificas (CSIC), Cantoblanco 28049,Madrid, Spain;

Institute de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigations Cientificas (CSIC), Cantoblanco 28049,Madrid, Spain;

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Synthesis of novel lidocaine-releasing poly(diol-co-citrate) elastomers by using deep eutectic solvents

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