A new strategy for designing a graphene oxide-based DNA hairpin probe: fluorescence upon switching the orientation of the sticky endt

摘要

Here we report a new strategy for designing a graphene oxide (GO)-quenched dye-labeled DNA hairpin probe by utilizing the sticky end adsorbed onto the GO surface. Only introduction of target DNA can alter the orientation of the sticky end, causing the dye to move apart from the GO surface, resulting in fluorescence restoration.