The different role of Cu~(++) and Zn~(++) ions in affecting the interaction of prion peptide PrP106-126 with model membranes

Domenico Grasso; Danilo Milardi; Carmelo La Rosa; Enrico Rizzarelli

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The different role of Cu~(++) and Zn~(++) ions in affecting the interaction of prion peptide PrP106-126 with model membranes

机译：Cu〜（++）和Zn〜（++）离子在影响病毒肽PrP106-126与模型膜相互作用中的不同作用

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Differential scanning calorimetric (DSC) experiments have shown that the ability of PrP106-126 to perturb 1,3-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) model membranes is differently affected by Cu~(++) and Zn~(++) ions.

机译：差示扫描量热（DSC）实验表明，PrP106-126扰动1,3-二棕榈酰-sn-甘油-3-磷酸胆碱（DPPC）模型膜的能力受Cu〜（++）和Zn〜（ ++）离子。

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来源
《Chemical Communications》 |2004年第2期|p.246-247|共2页
作者
Domenico Grasso; Danilo Milardi; Carmelo La Rosa; Enrico Rizzarelli;
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作者单位

Dipartimento di Scienze Chimiche, Universita di Catania, Viale Andrea Doria, 6 95125 Catania, Italy;

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正文语种 eng
中图分类化学;
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1. DSC study of the interaction of the prion peptide PrP106-126 with artificial membranes [J] . D.Grasso, D.Milardi, C.La Rosa, New Journal of Chemistry . 2001,第12期

机译：DSC研究pr病毒肽PrP106-126与人造膜的相互作用
2. The role of calcium ions in the interactions of PrP106-126 amide with model membranes [J] . Jian Zhong, Chunhui Yang, Wenfu Zheng, Colloids and Surfaces, B. Biointerfaces . 2010,第1期

机译：钙离子在PrP106-126酰胺与模型膜相互作用中的作用
3. Copper(II) interaction with unstructured prion domain outside the octarepeat region: Speciation, stability, and binding details of copper(II) complexes with PrP106-126 peptides [J] . Di Natale G, Grasso G, Impellizzeri G, Inorganic Chemistry: A Research Journal that Includes Bioinorganic, Catalytic, Organometallic, Solid-State, and Synthetic Chemistry and Reaction Dynamics . 2005,第20期

机译：铜（II）与八边形区域外的非结构化pr病毒域的相互作用：铜（II）与PrP106-126肽复合物的形态，稳定性和结合细节
4. ESI IN THE STUDY OF THE INTERACTIONS BETWEEN PHOSPHINO-CU(I) COMPLEXES AND CU(II) SALTS WITH MODEL PEPTIDES RELEVANT TO HUMAN COPPER TRANSPORTERS (HCTR) [C] . Francesco Tisato, Karolina Bossak-Ahmed, Marina Porchia, International Mass Spectrometry Conference . 2018

机译：ESI在研究磷氨酸-Cu（I）络合物和Cu（II）盐之间的相互作用，其与人铜转运蛋白相关的模型肽（HCTR）
5. Interactions of designed transmembrane alpha-helical model peptides with phospholipid bilayer model membranes [D] . Liu, Feng. 2004

机译：设计的跨膜α-螺旋模型肽与磷脂双层模型膜的相互作用
6. Prion Protein Does Not Confer Resistance to Hippocampus-Derived Zpl Cells against the Toxic Effects of Cu2+ Mn2+ Zn2+ and Co2+ Not Supporting a General Protective Role for PrP in Transition Metal Induced Toxicity [O] . Pradeep Kumar Reddy Cingaram, Antal Nyeste, Divya Teja Dondapati, -1

机译：Prion蛋白不能赋予海马衍生的Zpl细胞抗Cu2 +Mn2 +Zn2 +和Co2 +的毒性作用不支持PrP在过渡金属诱导的毒性中的一般保护作用。
7. Interaction of Cu(II)with His-Val-Gly-Asp and of Zn(II) with His-Val-His, Two Peptides at the Active Site of Cu,Zn-Superoxide Dismutase [O] . Myari, Alexandra, Malandrinos, Gerasimos, Plakatouras, John, 2003

机译：Cu（II）与His-Val-Gly-Asp和Zn（II）的相互作用与他的Val-His，两个肽在活性位点铜锌超氧化物歧化酶

The different role of Cu~(++) and Zn~(++) ions in affecting the interaction of prion peptide PrP106-126 with model membranes

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