Intramolecular alkene hydroaminations catalyzed by a bis(thiophosphinic amidate) Zr(IV) complex

摘要

A neutral Zr(IV) complex has been shown to be an effective precatalyst for intramolecular alkene hydroaminations that provide cyclic amines in good to excellent yields.The intramolecular hydroamination of alkenes constitutes a powerful method for the synthesis of azacycles.The seminal group 3 metallocenes developed by Marks and co-workers have recently been joined by a variety of non-metallocene complexes of the group 3 metals as catalysts for this important reaction.