Click chemistry: a new facile and efficient strategy for preparation of functionalized HPLC packings

摘要

Click chemistry has been successfully extended into the field of preparation of functionalized HPLC packings, proving a novel facile and efficient strategy for covalently bonding stationary phases onto HPLC grade silica beads; the potential has been demonstrated by the preparation of "Click I - IV'' columns and preliminary results in the separation of sugars.