Screening for crystalline salts via mechanochemistry

Andrew V.Trask; Delia A.Haynes; W.D.Samuel Motherwell; William Jones

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Screening for crystalline salts via mechanochemistry

机译：通过机械化学筛选结晶盐

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摘要

Neat grinding and solvent-drop grinding methods are found to be effective screening tools for indicating the potential for crystalline salt formation involving a given acid-base pair,as demonstrated with two model Pharmaceuticals.

机译：如两个模型制药公司所证明的，发现整洁的研磨和溶剂滴磨的方法是有效的筛选工具，用于指示涉及给定酸碱对的结晶盐形成的潜力。

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来源
《Chemical Communications》 |2006年第1期|p.51-53|共3页
作者
Andrew V.Trask; Delia A.Haynes; W.D.Samuel Motherwell; William Jones;
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作者单位

Pfizer Institute for Pharmaceutical Materials Science,Department of Chemistry,University of Cambridge,Lensfield Road,Cambridge,UK Cm 1EW;

Pfizer Institute for Pharmaceutical Materials Science,Department of Chemistry,University of Cambridge,Lensfield Road,Cambridge,UK Cm 1EW;

Cambridge Crystallographic Data Centre,12 Union Road,Cambridge,UK CB2 1EZ;

Pfizer Institute for Pharmaceutical Materials Science,Department of Chemistry,University of Cambridge,Lensfield Road,Cambridge,UK Cm 1EW;

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正文语种 eng
中图分类化学;
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入库时间 2022-08-17 13:29:33

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Screening for crystalline salts via mechanochemistry

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