New Mechanistic Insights in the Cytochrome P-450 Model Reactions: Direct Identification of the Reactive Intermediates

摘要

In CH3CN–H20 medium the porphyrin Fe(IV)=O and porphyrin-C6F5IO adduct, and tBu $dot{hbox{O}}$ /tBuO $dot{hbox{O}}$ radicals have been spectroscopically identified. The involvement of multiple reactive intermediates in C6F5IO oxidizing system has also been demonstrated.