Heart Protection by Combination Therapy with Esmolol and Milrinone at Late-Ischemia and Early Reperfusion

Ming-He Huang; Yewen Wu; Vincent Nguyen; Saurabh Rastogi; Bradley K. McConnell; Cori Wijaya; Barry F. Uretsky; Kian-Keong Poh; Huay-Cheem Tan; Kenichi Fujise

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Heart Protection by Combination Therapy with Esmolol and Milrinone at Late-Ischemia and Early Reperfusion

机译：埃司莫尔和米力农联合治疗晚期缺血和早期再灌注对心脏的保护

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Introduction The present study determined whether late-ischemia/early reperfusion therapy with the β₁-adrenergic receptor (AR) blocker esmolol and phosphodiesterase III inhibitor milrinone reduced left ventricular (LV) myocardial infarct size (IS).

机译：前言本研究确定了β_{1 -肾上腺素能受体（AR）阻断剂艾司洛尔和磷酸二酯酶III抑制剂米力农晚期缺血/早期再灌注治疗是否能降低左心室（LV）心肌梗死面积（IS）。}

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《Cardiovascular Drugs and Therapy》 |2011年第3期|p.223-232|共10页
作者
Ming-He Huang; Yewen Wu; Vincent Nguyen; Saurabh Rastogi; Bradley K. McConnell; Cori Wijaya; Barry F. Uretsky; Kian-Keong Poh; Huay-Cheem Tan; Kenichi Fujise;
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正文语种 eng
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Akt – Esmolol – Milrinone – PKA – Reperfusion injury;

机译：Akt –艾司洛尔–米力农– PKA –再灌注损伤;

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专利

1. Heart protection by combination therapy with esmolol and milrinone at late-ischemia and early reperfusion. [J] . Huang MH, Wu Y, Nguyen V, Cardiovascular drugs and therapy . 2011,第3期

机译：在缺血晚期和早期再灌注时，与艾司洛尔和米力农联合治疗可保护心脏。
2. Combination therapy with milrinone and esmolol for heart protection in patients with severe sepsis: a prospective, randomized trial. [J] . Zenggeng Wang, Qinghua Wu, Xiangbi Nie, Clinical drug investigation . 2015,第11期

机译：米力农和艾司洛尔联合治疗对严重脓毒症患者的心脏保护作用：一项前瞻性随机试验。
3. Safety of combination therapy with milrinone and esmolol for heart protection during percutaneous coronary intervention in acute myocardial infarction [J] . PohK.-K., XuX., ChanM.Y., European journal of clinical pharmacology . 2014,第5期

机译：米力农和艾司洛尔联合治疗急性心肌梗死经皮冠状动脉介入治疗期间心脏保护的安全性
4. Milrinone Administered Just After but not 20 min After Reperfusion Protects against Myocardial Stunning in Swine [C] . Itsuko Shibata, Osamu Yoshitomi, Kazuyuki Sakai, ASEAN Congress of Anesthesiologists . 2009

机译：在再灌注后20分钟后，米兰诺酮在再灌注后免受猪心肌令人惊叹
5. Combination immunotherapy for early and continuous protection from methamphetamine pharmacological effects [D] . Hambuchen, Michael D. 2013

机译：联合免疫疗法可早期和连续保护免受甲基苯丙胺药理作用
6. Heart Protection by Combination Therapy with Esmolol and Milrinone at Late-Ischemia and Early Reperfusion [O] . Ming-He Huang, Yewen Wu, Vincent Nguyen, -1

机译：埃司莫尔和米力农联合治疗晚期缺血和早期再灌注对心脏的保护
7. Heart Protection by Combination Therapy with Esmolol and Milrinone at Late-Ischemia and Early Reperfusion [O] . Ming-He Huang, Yewen Wu, Vincent Nguyen, 2011

机译：埃司莫尔和米力农联合治疗晚期缺血和早期再灌注对心脏的保护

Heart Protection by Combination Therapy with Esmolol and Milrinone at Late-Ischemia and Early Reperfusion

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