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Merck Wants to Put an End to Counting Sheep

机译:默克公司希望杜绝数羊

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A sleeping pill that offers the snooze-inducing benefits of Ambien and Lunesta while avoiding next-day grogginess and disorientation has eluded drug heavyweights including GlaxoSmithKline and Japan's Takeda Pharmaceutical. Merck thinks it may have found a solution.rnThe drugmaker is in final testing of an insomnia product, named suvorex-ant, that works differently from the market leaders. Rather than boostingrnthe brain's complex sleep system, su-vorexant uses a more precise approach to block a tiny group of receptors that keep the body alert.rnIf approved by the Food and Drug Administration, the pill could generate $900 million annually for Merck, according to Barclays analyst Tony Butler. "It's not whether you put the patient to sleep, it's how you feel the next day," says Rafael Pelayo, a professor at the Stanford Center for Sleep Sciences and Medicine.
机译:一种安眠药具有Ambien和Lunesta的延缓睡眠的功效,同时又避免了第二天的烦躁和迷失方向,因此包括葛兰素史克(GlaxoSmithKline)和日本武田制药(Takeda Pharmaceutical)等重量级药物都无法使用。默克公司(Merck)认为可能找到了解决方案。该制药商正在对一种名为suvorex-ant的失眠产品进行最终测试,该产品的作用与市场领导者不同。 su-vorexant并没有增强大脑复杂的睡眠系统,而是采用了更精确的方法来阻止一小部分使身体保持警觉的受体。如果得到食品和药物管理局的批准,这种药每年可以为默克公司带来9亿美元的收入。巴克莱分析师托尼·巴特勒。斯坦福大学睡眠科学与医学中心教授拉斐尔·佩拉约(Rafael Pelayo)说:“这不关乎让患者入睡,而是第二天的感觉。”

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