Inhibitory effect and mechanism of acarbose combined with gymnemic acid on maltose absorption in rat intestine

摘要

AIM To compare the combinative and individual effect of acarbose and gymnemic acid (GA) on maltose absorption and hydrolysis in small intestine to determine whether nutrient control in diabetic care can be improved by combination of them. METHODS The absorption and hydrolysis of Maltose were studied by cyclic perfusion of Intestinal loops in situ and motility of the Intestine was recorded with the intestinal ring in Vitro using Wistar rats.