Failure of normalisation of α fetoprotein concentration after successful treatment of teratoma

摘要

The development of successful treatment regimens for germ cell tumours has been one of the important advances in cancer chemotherapy. The effects of such treatment are monitored by measurement of serum concentrations of the tumour markers α fetoprotein and human chorionic gonadotrophin, as well as clinical and radiological assessment. The persistence of raised concentrations of α fetoprotein during or after treatment requires urgent investigation to delineate teratoma resistant to chemotherapy.