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Fluoridation, fractures, and teeth

机译:氟化,骨折和牙齿

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摘要

The benefits to teeth of fluoridating community water supplies are widely acknowledged. A comprehensive summary of the most recent evidence is included in the systematic review by McDonagh et al in this issue of the journal (p 855) but some concerns persist about possible adverse effects on bone. The paper by Phipps et al in this issue of the BMJ (p 860) introduces new evidence on the safety of fluoridating community water supplies. In their multi-centre prospective study, Phipps et al found that ambulatory women aged 65 years or older who had been continuously exposed to fluoridated water for the past 20 years had higher bone mineral density at the lumbar spine and hip and a slightly lower risk of hip and vertebral fractures than women who had not been exposed to fluoridated water. The potential confounding effect of other factors known to be associated with fractures, such as oestrogen use, smoking, and body weight, was controlled for at the level of the individual woman.
机译:氟化社区供水对牙齿的好处已广为人知。 McDonagh等人在本期杂志中对系统性综述进行了全面总结,总结了最新证据(第855页),但仍存在一些可能对骨骼产生不利影响的担忧。 Phipps等人在本期《 BMJ》中的论文(第860页)介绍了氟化社区供水的安全性的新证据。在他们的多中心前瞻性研究中,Phipps等人发现,在过去20年中连续暴露于氟化水中的65岁或65岁以上的非卧床女性,其腰椎和髋部的骨矿物质密度较高,罹患乳糜泻的风险略低。臀部和椎骨骨折的女性比未曾接触过氟化水的女性要多。已知与骨折相关的其他因素(例如使用雌激素,吸烟和体重)的潜在混杂效应被控制在单个女性的水平上。

著录项

  • 来源
    《British Medical Journal》 |2000年第7265期|p.844-845|共2页
  • 作者

    Hannu W Hausen;

  • 作者单位
  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 医药、卫生;
  • 关键词

  • 入库时间 2022-08-18 00:12:58

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