Inhibitory effects of ω-3 polyunsaturated fatty acids on receptor- mediated non-selective cation currents in rat A7r5 vascular smooth muscle cells

摘要

These results demonstrate that ω-3 polyunsaturated fatty acids can activate a K~+ current and also effectively inhibit receptor-mediated non-selective cation currents in rat A7r5 vascular smooth muscle cells. Thus, the data suggest that ω-3 fatty acids may play an important role in the regulation of vascular tone.