A dodecapeptide deduced from cytokeratin sequence strongly enhances uPA/tPA-mediated plasminogen activation

Nata#x161; a Obermajer; Bojan Doljak; Jure Pohleven; Janko Kos

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A dodecapeptide deduced from cytokeratin sequence strongly enhances uPA/tPA-mediated plasminogen activation

机译：由细胞角蛋白序列推导的十二肽强烈增强uPA / tPA介导的纤溶酶原激活

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《British Journal of Haematology》 |2010年第1期|p.121-123|共3页
作者
Nata#x161; a Obermajer; Bojan Doljak; Jure Pohleven; Janko Kos;
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Department of Biotechnology, Jož

ef Stefan Institute|Faculty of Pharmacy, Department of Pharmaceutical Biology, University of Ljubljana, Ljubljana, Slovenia. E-mail: natasa.obermajer@ffa.uni-lj.si;

Faculty of Pharmacy, Department of Pharmaceutical Biology, University of Ljubljana, Ljubljana, Slovenia. E-mail: natasa.obermajer@ffa.uni-lj.si;

Department of Biotechnology, Jož

ef Stefan Institute;

Department of Biotechnology, Jož

ef Stefan Institute|Faculty of Pharmacy, Department of Pharmaceutical Biology, University of Ljubljana, Ljubljana, Slovenia. E-mail: natasa.obermajer@ffa.uni-lj.si;

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机译：尿激酶型纤溶酶原激活物（uPA）和整联蛋白αv beta 3的kringle域的直接相互作用诱导信号转导并增强纤溶酶原的激活。
2. MUC1 Protein Induces Urokinase-type Plasminogen Activator (uPA) by Forming a Complex with NF-κB p65 Transcription Factor and Binding to the uPA Promoter, Leading to Enhanced Invasiveness of Cancer Cells [J] . Yugo Mori, Kaoru Akita, Shuhei Tanida, The Journal of biological chemistry . 2014,第51期

机译：Muc1蛋白通过与NF-κBP65转录因子形成复合物并与UPA启动子结合，诱导尿激酶型纤溶酶原激活物（UPA），导致癌细胞的增强侵入性
3. Synergistic transcriptional activation of the mouse urokinase plasminogen activator (uPA) gene and of its enhancer activator protein 1 (AP1) site by cAMP and retinoic acid [J] . Mira-Y-Lopez R., Jing YK., Jaramillo S. The Biochemical Journal . 1998,第Pta3期

机译：cAMP和视黄酸对小鼠尿激酶纤溶酶原激活物（uPA）基因及其增强子活化蛋白1（AP1）位点的协同转录激活
4. GLYCATED COLLAGEN DECREASES UROKINASE PLASMINOGEN ACTIVATOR (UPA) ACTIVITY IN ENDOTHELIAL CELLS [C] . Justin G. Mathew, Alisa Morss Clyne ASME summer bioengineering conference;SBC2012 . 2012

机译：糖化胶原蛋白降低内皮细胞中尿激酶纤溶酶原激活物（UPA）的活性
5. Tissue plasminogen activator & plasminogen system in Chondroitinase-mediated axonal plasticity [D] . Bukhari, Noreen 2010

机译：软骨素酶介导的轴突可塑性中的组织纤溶酶原激活物和纤溶酶原系统
6. MUC1 Protein Induces Urokinase-type Plasminogen Activator (uPA) by Forming a Complex with NF-κB p65 Transcription Factor and Binding to the uPA Promoter Leading to Enhanced Invasiveness of Cancer Cells [O] . Yugo Mori, Kaoru Akita, Shuhei Tanida, 2014

机译：MUC1蛋白通过与NF-κBp65转录因子形成复合物并与uPA启动子结合诱导尿激酶型纤溶酶原激活物（uPA）导致癌细胞侵袭性增强。
7. A dodecapeptide deduced from cytokeratin sequence strongly enhances uPA/tPA-mediated plasminogen activation [O] . Pohleven Jure, Doljak Bojan, Obermajer Nataša, 2015

机译：由细胞角蛋白序列推导的十二肽强烈增强uPA / tPA介导的纤溶酶原激活

A dodecapeptide deduced from cytokeratin sequence strongly enhances uPA/tPA-mediated plasminogen activation

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