Quality of Life Analyses in a Clinical Trial of DPPE (tesmilifene) Plus Doxorubicin Versus Doxorubicin in Patients with Advanced or Metastatic Breast Cancer: NCIC CTG Trial MA.19

Jianhua Liu; Dongsheng Tu; Janet Dancey; Leonard Reyno; Kathleen I. Pritchard; Joseph Pater; Lesley K Seymour

首页> 外文期刊>Breast Cancer Research and Treatment >Quality of Life Analyses in a Clinical Trial of DPPE (tesmilifene) Plus Doxorubicin Versus Doxorubicin in Patients with Advanced or Metastatic Breast Cancer: NCIC CTG Trial MA.19

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Quality of Life Analyses in a Clinical Trial of DPPE (tesmilifene) Plus Doxorubicin Versus Doxorubicin in Patients with Advanced or Metastatic Breast Cancer: NCIC CTG Trial MA.19

机译：在晚期或转移性乳腺癌患者中进行DPPE（tesmilifene）加阿霉素与阿霉素的临床试验中的生活质量分析：NCIC CTG试验MA.19

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DPPE (tesmilifene) plus doxorubicin (DOX) demonstrated a significant improvement in survival versus DOX in a phase III clinical trial in advanced breast cancer. However, DPPE is associated with unusual toxicity in the form of hallucinations, nausea and vomiting which were anticipated to impact on short-term quality of life (QOL).

机译：在晚期乳腺癌的III期临床试验中，DPPE（替米尼芬）加阿霉素（DOX）与DOX相比，生存率显着提高。然而，DPPE与幻觉，恶心和呕吐等形式的异常毒性相关，预计会影响短期生活质量（QOL）。

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《Breast Cancer Research and Treatment》 |2006年第3期|263-271|共9页
作者
Jianhua Liu; Dongsheng Tu; Janet Dancey; Leonard Reyno; Kathleen I. Pritchard; Joseph Pater; Lesley K Seymour;
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作者单位

National Cancer Institute of Canada Clinical Trials Group Cancer Research Institute Queens University;

National Cancer Institute of Canada Clinical Trials Group Cancer Research Institute Queens University;

National Cancer Institute of Canada Clinical Trials Group Cancer Research Institute Queens University;

National Cancer Institute of Canada Clinical Trials Group Cancer Research Institute Queens University;

National Cancer Institute of Canada Clinical Trials Group Cancer Research Institute Queens University;

National Cancer Institute of Canada Clinical Trials Group Cancer Research Institute Queens University;

National Cancer Institute of Canada Clinical Trials Group Cancer Research Institute Queens University;

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原文格式 PDF
正文语种 eng
中图分类
关键词
Quality of life; Analyses; Statistical methods; DPPE; Breast cancer; Tesmilifene;

机译：生活质量;分析;统计方法;DPPE;乳腺癌;Tesmilifene;

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1. Quality of Life Analyses in a Clinical Trial of DPPE (tesmilifene) Plus Doxorubicin Versus Doxorubicin in Patients with Advanced or Metastatic Breast Cancer: NCIC CTG Trial MA.19. [J] . Liu J, Tu D, Dancey J, Breast cancer research and treatment. . 2006,第3期

机译：在晚期或转移性乳腺癌患者中进行DPPE（tesmilifene）加阿霉素与阿霉素的临床试验中的生活质量分析：NCIC CTG试验MA.19。
2. Randomized, controlled trial investigating short-term health-related quality of life with doxorubicin and paclitaxel versus doxorubicin and cyclophosphamide as first-line chemotherapy in patients with metastatic breast cancer: European Organization f [J] . Bottomley A, Biganzoli L, Cufer T, Journal of Clinical Oncology . 2004,第13期

机译：研究阿霉素和紫杉醇与阿霉素和环磷酰胺作为转移性乳腺癌患者一线化疗的短期健康相关生活质量的随机对照试验：欧洲组织f
3. Phase II to III study comparing doxorubicin and docetaxel with fluorouracil, doxorubicin, and cyclophosphamide as first-line chemotherapy in patients with metastatic breast cancer: results of a Dutch Community Setting Trial for the Clinical Trial Gro [J] . Bontenbal M, Creemers GJ, Braun HJ, Journal of Clinical Oncology . 2005,第28期

机译：II至III期研究比较阿霉素和多西紫杉醇与氟尿嘧啶，阿霉素和环磷酰胺作为转移性乳腺癌患者的一线化疗：荷兰社区临床试验设置的结果Gro
4. Effects of laser immunotherapy on late-stage, metastatic breast cancer patients in a Phase Ⅱ clinical trial [C] . Gabriela L. Ferrel, Feifan Zhou, Xiaosong Li, Biophotonics and immune responses IX . 2014

机译：Ⅱ期临床试验中激光免疫疗法对晚期转移性乳腺癌患者的影响
5. Analysis of quality of life data from a clinical trial in patients with advanced breast cancer with a comparison of different statistical approaches. [D] . Liu, Jianhua. 2002

机译：通过比较不同统计方法对晚期乳腺癌患者的临床试验的生活质量数据进行分析。
6. Phase II Clinical Trial With Pegylated Liposomal Doxorubicin(CAELYX®/Doxil®) and Quality of Life Evaluation (EORTC QLQ-C30)in Adult Patients With Advanced Soft Tissue Sarcomas: A study of the Spanish Group for Research in Sarcomas (GEIS) [O] . A. Poveda, A. López-Pousa, J. Martín, 2005

机译：聚乙二醇化脂质体阿霉素的II期临床试验（CAELYX®/Doxil®）和生活质量评估（EORTC QLQ-C30）晚期软组织肉瘤成年患者的治疗：西班牙肉瘤研究小组（GEIS）的研究
7. Health-related quality of life in patients with advanced colorectal cancer treated with cetuximab: Overall and KRAS-specific results of the NCIC CTG and AGITG CO.17 Trial [O] . Au, Heather-Jane, Karapetis, Christos S., Ou27Callaghan, Chris J., 2009

机译：西妥昔单抗治疗的晚期大肠癌患者的健康相关生活质量：NCIC CTG和AGITG CO.17的总体和KRAS特异性结果

Quality of Life Analyses in a Clinical Trial of DPPE (tesmilifene) Plus Doxorubicin Versus Doxorubicin in Patients with Advanced or Metastatic Breast Cancer: NCIC CTG Trial MA.19

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