1H, 13C and 15N backbone assignments for the ligand binding domain of the Pseudomonas aeruginosa virulence regulator LasR

摘要

LasR regulates toxin production in Pseudomonas aeruginosa and its inhibition can attenuate the virulence of this opportunistic human pathogen. To aid studies of interactions with inhibitors, we report the NMR backbone assignments for the dimeric LasR ligand-binding domain.