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Lab-on-a-Chip Technology for Environmental Monitoring of Microorganisms

机译:微生物环境监测的芯片实验室技术

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摘要

Improved environmental monitoring of microorganisms is currently an important issue, since traditional detection methods are costly and time consuming (often requiring 2-3 days). In contrast, microfluidic chip-based technologies provide promising alternatives. The presence of environmental contaminants, especially bacterial, viral, and parasitic pathogens and their toxins, is creating a major public health problem. The detection of microbial communities in environmental samples is the first step to recognizing these organisms and insuring health and safety against their infection. This review addresses both the existing and innovative technologies for the detection of pathogens present in the environmental samples. First, impacts and challenges related to pathogens in the environmental samples are discussed, and standard techniques for their identification are addressed. Next, the microfluidic technologies are introduced as an alternative strategy with a particular focus on the detection of environmental contaminants. Challenges that still need to be overcome are also discussed. The review concludes with a section on paper-based microfluidic device and a discussion on future prospects.
机译:由于传统的检测方法成本高昂且耗时(通常需要2-3天),因此改善微生物的环境监测目前是一个重要的问题。相反,基于微流体芯片的技术提供了有希望的替代方案。环境污染物的存在,特别是细菌,病毒和寄生性病原体及其毒素的存在,正在造成一个重大的公共卫生问题。检测环境样品中的微生物群落是识别这些生物并确保其健康和安全性免受感染的第一步。这篇综述涉及检测环境样品中存在的病原体的现有技术和创新技术。首先,讨论了与环境样品中的病原体有关的影响和挑战,并讨论了用于鉴定其的标准技术。接下来,引入微流体技术作为替代策略,特别关注环境污染物的检测。还讨论了仍然需要克服的挑战。审查以关于纸基微流控设备的部分以及对未来前景的讨论作为结尾。

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