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Comparison of organ dosimetry methods and effective dose calculation methods for paediatric CT

机译:儿科CT的器官剂量学方法与有效剂量计算方法的比较

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摘要

Computed tomography (CT) is the single biggest ionising radiation risk from anthropogenic exposure. Reducing unnecessary carcinogenic risks from this source requires the determination of organ and tissue absorbed doses to estimate detrimental stochastic effects. In addition, effective dose can be used to assess comparative risk between exposure situations and facilitate dose reduction through optimisation. Children are at the highest risk from radiation induced carcinogenesis and therefore dosimetry for paediatric CT recipients is essential in addressing the ionising radiation health risks of CT scanning. However, there is no well-defined method in the clinical environment for routinely and reliably performing paediatric CT organ dosimetry and there are numerous methods utilised for estimating paediatric CT effective dose. Therefore, in this study, eleven computational methods for organ dosimetry and/or effective dose calculation were investigated and compared with absorbed doses measured using thermolu-minescent dosemeters placed in a physical anthropomorphic phantom representing a 10 year old child. Three common clinical paediatric CT protocols including brain, chest and abdomen/pelvis examinations were evaluated. Overall, computed absorbed doses to organs and tissues fully and directly irradiated demonstrated better agreement (within approximately 50 %) with the measured absorbed doses than absorbed doses to distributed organs or to those located on the periphery of the scan volume, which showed up to a 15-fold dose variation. The disparities predominantly arose from differences in the phantoms used. While the ability to estimate CT dose is essential for risk assessment and radiation protection, identifying a simple, practical dosimetry method remains challenging.
机译:计算机断层扫描(CT)是人为暴露造成的最大的电离辐射风险。为了减少这种来源的不必要的致癌风险,需要确定器官和组织的吸收剂量,以估计有害的随机效应。此外,有效剂量可用于评估暴露情况之间的比较风险,并通过优化促进剂量减少。儿童受放射线致癌的风险最高,因此,针对儿童CT接受者的剂量测定对于解决CT扫描的电离辐射健康风险至关重要。但是,在临床环境中,没有一种常规且可靠地进行儿科CT器官剂量测定的明确方法,并且有许多方法可用于估算儿科CT有效剂量。因此,在这项研究中,研究了用于器官剂量测定和/或有效剂量计算的11种计算方法,并将其与使用代表代表10岁儿童的物理拟人模型中的热致发光剂量计测量的吸收剂量进行了比较。评估了三种常见的儿科CT常规临床方案,包括脑,胸部和腹部/骨盆检查。总体而言,计算得出的完全和直接照射到器官和组织的吸收剂量与测得的吸收剂量相比,对分布的器官或位于扫描体积外围的那些器官的吸收剂量具有更好的一致性(在大约50%之内)。 15倍剂量变化。差异主要是由于所使用的幻像的差异引起的。虽然估计CT剂量的能力对于风险评估和辐射防护至关重要,但是确定一种简单实用的剂量学方法仍然具有挑战性。

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