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The dynamical model for COVID-19 with asymptotic analysis and numerical implementations

机译:Covid-19具有渐近分析的动态模型和数值实现

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The 2019 novel coronavirus (COVID-19) emerged at the end of 2019 has a great impact on China and all over the world. The transmission mechanism of COVID-19 is still unclear. Except for the initial status and the imported cases, the isolation measures and the medical treatments of the infected patients have essential influences on the spread of COVID-19. In this paper, we establish a mathematical model for COVID-19 transmission involving the interactive effect of various factors for the infected people, including imported cases, isolating rate, diagnostic rate, recovery rate and also the mortality rate. Under the assumption that the random incubation period, the cure period and the diagnosis period are subject to the Weibull distribution, the quantity of daily existing infected people is finally governed by a linear integral-differential equation with convolution kernel. Based on the asymptotic behavior and the quantitative analysis on the model, we rigorously prove that, for limited external input patients, both the quantity of infected patients and its variation ratio will finally tend to zero, if the infected patients are sufficiently isolated or the infection rate is small enough. Finally, numerical performances for the proposed model as well as the comparisons between our simulations and the clinical data of the city Wuhan and Italy are demonstrated, showing the validity of our model with suitably specified model parameters.
机译:2019年2019年的2019年新型冠状病毒(Covid-19)在2019年底出现了对中国和世界各地的影响很大。 Covid-19的传动机制尚不清楚。除初始状况和进口病例外,感染患者的隔离措施和医疗治疗对Covid-19的传播有必要的影响。在本文中,我们建立了Covid-19传播的数学模型,涉及感染者各种因素的互动效果,包括进口病例,隔离率,诊断率,回收率以及死亡率。在假设随机孵化期,治愈期和诊断期间受到威布尔分布的影响,每日现有受感染者的数量最终通过与卷积内核的线性积分 - 微分方程来控制。基于渐近行为和模型的定量分析,我们严格证明,对于有限的外部输入患者,感染患者的数量及其变异比率将最终趋于零,如果感染的患者足够分离或感染速率足够小。最后,展示了拟议模型的数值表现以及我们的模拟与武汉和意大利临床数据的比较,显示了我们的模型的有效性,具有适当指定的模型参数。

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