The phrase "little did he know" plays a critical role in the movie Stranger than Fiction, starring Will Farrell. In the film, Dustin Hoffman's character, a literature expert, explains that "little did he know" is a very powerful literary device that can have great implications for the character involved. It generally means that there is some huge change (usually bad) that is about to befall the poor wretch and about which he is completely unaware.
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