...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Annals of Surgical Oncology >Overexpression of Axin Downregulates TCF-4 and Inhibits the Development of Lung Cancer
【24h】

Overexpression of Axin Downregulates TCF-4 and Inhibits the Development of Lung Cancer

机译：毒素的过表达下调TCF-4并抑制肺癌的发展

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

T cell factor 4 (TCF-4) mediates a nuclear response to wingless/int (Wnt) signals by interacting with β-catenin. Axis inhibition protein (axin) is an important negative regulator of the Wnt signaling pathway. Our aims were to examine the relationship between axin and TCF-4 and to explore the effects of axin on the development of lung cancer.
机译：T细胞因子4（TCF-4）通过与β-catenin相互作用介导对无翅/ int（Wnt）信号的核反应。轴抑制蛋白（毒素）是Wnt信号通路的重要负调控因子。我们的目的是检查毒素与TCF-4之间的关系，并探讨毒素对肺癌发展的影响。

著录项

  • 来源
    《Annals of Surgical Oncology》 |2007年第11期|3251-3259|共9页
  • 作者

    Hong-Tao Xu MD PhD; Qiang Wei MD PhD; Yang Liu MD PhD; Lian-He Yang MD; Shun-Dong Dai MD PhD; Yang Han MD PhD; Juan-Han Yu MD; Nan Liu MD; En-Hua Wang MD PhD;

  • 作者单位

    Department of Pathology College of Basic Medical Sciences China Medical University and Department of Pathology the First Affiliated Hospital of China Medical University Shenyang 110001 China;

    Department of Pathology College of Basic Medical Sciences China Medical University and Department of Pathology the First Affiliated Hospital of China Medical University Shenyang 110001 China;

    Department of Pathology College of Basic Medical Sciences China Medical University and Department of Pathology the First Affiliated Hospital of China Medical University Shenyang 110001 China;

    Department of Pathology College of Basic Medical Sciences China Medical University and Department of Pathology the First Affiliated Hospital of China Medical University Shenyang 110001 China;

    Department of Pathology College of Basic Medical Sciences China Medical University and Department of Pathology the First Affiliated Hospital of China Medical University Shenyang 110001 China;

    Department of Pathology College of Basic Medical Sciences China Medical University and Department of Pathology the First Affiliated Hospital of China Medical University Shenyang 110001 China;

    Department of Pathology College of Basic Medical Sciences China Medical University and Department of Pathology the First Affiliated Hospital of China Medical University Shenyang 110001 China;

    Department of Pathology College of Basic Medical Sciences China Medical University and Department of Pathology the First Affiliated Hospital of China Medical University Shenyang 110001 China;

    Department of Pathology College of Basic Medical Sciences China Medical University and Department of Pathology the First Affiliated Hospital of China Medical University Shenyang 110001 China;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Axin; T cell factor 4; Lung cancer; Proliferation; Invasion;

    机译：毒素;T细胞因子4;肺癌;增殖;侵袭;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号