Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer

D. -W. Kim12 S. -Y. Kim3 H. -K. Kim4 S. -W. Kim5 S. W. Shin6 J. S. Kim7 K. Park8 M. Y. Lee9 and D. S. Heo12

首页> 外文期刊>Annals of Oncology >Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer

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Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer

机译：Genexol-PM的多中心II期临床试验，这是一种新型的无Cremophor的紫杉醇聚合物胶束与紫杉醇联合顺铂治疗晚期非小细胞肺癌患者

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Background: Genexol-PM is a novel Cremophor EL (CrEL)-free polymeric micelle formulation of paclitaxel (Taxol). This multicenter phase II study was designed to evaluate the efficacy and safety of the combination of Genexol-PM and cisplatin for the treatment of advanced non-small-cell lung cancer (NSCLC).

机译：背景：Genexol-PM是一种新的不含紫杉醇（Taxol）的不含Cremophor EL（CrEL）的聚合物胶束制剂。这项多中心II期研究旨在评估Genexol-PM和顺铂联合治疗晚期非小细胞肺癌（NSCLC）的有效性和安全性。

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《Annals of Oncology》 |2007年第12期|2009-2014|共6页
作者
D. -W. Kim12 S. -Y. Kim3 H. -K. Kim4 S. -W. Kim5 S. W. Shin6 J. S. Kim7 K. Park8 M. Y. Lee9 and D. S. Heo12;
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Department of Internal Medicine Seoul National University Hospital Seoul;

Cancer Research Institute Seoul National University College of Medicine Seoul;

Department of Internal Medicine Kyung Hee University Hospital Seoul;

Department of Internal Medicine St Vincent's Hospital Suwon;

Department of Internal Medicine Asan Medical Center Seoul;

Department of Internal Medicine Korea University Anam Hospital Seoul;

Department of Internal Medicine Korea University Guro Hospital Seoul;

Department of Medicine Samsung Medical Center Seoul;

Samyang Corporation Seoul Korea;

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1. Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer. [J] . Kim DW, Kim SY, Kim HK, Annals of oncology: official journal of the European Society for Medical Oncology . 2007,第12期

机译：Genexol-PM的多中心II期临床试验，这是一种新颖的不含Cremophor的紫杉醇聚合物胶束制剂，与顺铂联合用于晚期非小细胞肺癌患者。
2. Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer. [J] . Lee KS, Chung HC, Im SA, Breast cancer research and treatment. . 2008,第2期

机译：Genexol-PM（一种不含Cremophor的紫杉醇聚合物胶束制剂）的多中心II期临床试验，用于转移性乳腺癌患者。
3. Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer [J] . Keun Seok Lee, Hyun Cheol Chung, Seock Ah Im, Breast Cancer Research and Treatment . 2008,第2期

机译：Genexol-PM（一种无Cremophor的紫杉醇聚合物胶束制剂）的多中心II期临床试验，用于转移性乳腺癌患者
4. Phase I/II clinical trials on the effect of weekly paclitaxel (wPTX) and wPTX containing combination regimens for advanced and metastatic gastric cancer -ECRIN group studies [C] . Sakamoto J, Kodera Y, Kobayashi M, International Gastric Cancer Congress . 2009

机译：I / II期临床试验关于每周紫杉醇（WPTX）和WPTX含有晚期和转移性胃癌组合方案的临床试验 - 分泌组研究
5. The effectiveness of chemoradiation for stage III non-small-cell lung cancer patients at the Kingston Regional Cancer Center (Ontario). [D] . Sinclair, Suzanne Marie. 2003

机译：金斯敦地区癌症中心（安大略省）对III期非小细胞肺癌患者进行化学放射治疗的有效性。
6. An open-label multicenter phase I trial of a cremophor-free polymeric micelle formulation of paclitaxel combined with carboplatin as a first-line treatment for advanced ovarian cancer: a Korean Gynecologic Oncology Group study (KGOG-3016) [O] . Shin-Wha Lee, Yong-Man Kim, Young Tae Kim, 2017

机译：开放式多中心无紫杉醇紫杉醇与卡铂联合作为晚期卵巢癌的一线治疗的聚合物胶束制剂的I期临床试验：韩国妇科肿瘤小组研究（KGOG-3016）
7. Phase III randomised trial comparing paclitaxel/carboplatin with paclitaxel/cisplatin in patients with advanced non-small-cell lung cancer: a cooperative multinational trial [O] . Rosell, R., Gatzemeier, U., Betticher, D. C., 2017

机译：紫杉醇/卡铂与紫杉醇/顺铂在晚期非小细胞肺癌患者中进行比较的III期随机试验：一项合作的跨国试验

Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer

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