Clinical evidence of a graft-versus-lymphoma effect against relapsed diffuse large B-cell lymphoma after allogeneic hematopoietic stem-cell transplantation

M. R. Bishop1 R. M. Dean12 S. M. Steinberg3 J. Odom1 S. Z. Pavletic1 C. Chow4 S. Pittaluga5 C. Sportes1 N. M. Hardy1 J. Gea-Banacloche1 A. Kolstad6 R. E. Gress1 and D. H. Fowler1

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Clinical evidence of a graft-versus-lymphoma effect against relapsed diffuse large B-cell lymphoma after allogeneic hematopoietic stem-cell transplantation

机译：异基因造血干细胞移植后移植物抗淋巴瘤对复发性弥漫性大B细胞淋巴瘤的临床证据

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Background: A graft-versus-lymphoma effect against diffuse large B-cell lymphoma (DLBCL) is inferred by sustained relapse-free survival after allogeneic stem-cell transplantation; however, there are limited data on a direct graft-versus-lymphoma effect against DLBCL following immunotherapeutic intervention by either withdrawal of immunosuppression or donor lymphocyte infusion (DLI).

机译：背景：同种异体干细胞移植后持续的无复发存活可推断出移植物抗淋巴瘤对弥漫性大B细胞淋巴瘤（DLBCL）的作用。然而，关于通过撤消免疫抑制或输注供体淋巴细胞（DLI）进行免疫治疗干预后，直接移植物抗淋巴瘤对DLBCL的直接作用的数据有限。

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《Annals of Oncology》 |2008年第11期|1935-1940|共6页
作者
M. R. Bishop1 R. M. Dean12 S. M. Steinberg3 J. Odom1 S. Z. Pavletic1 C. Chow4 S. Pittaluga5 C. Sportes1 N. M. Hardy1 J. Gea-Banacloche1 A. Kolstad6 R. E. Gress1 and D. H. Fowler1;
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Experimental Transplantation and Immunology Branch Center for Cancer Research National Cancer Institute National Institutes of Health Bethesda MD;

Cleveland Clinic Foundation Cleveland OH;

Biostatistics and Data Management Section Center for Cancer Research National Cancer Institute;

Diagnostic Radiology Department Warren G. Magnuson Clinical Center;

Laboratory of Pathology Center for Cancer Research National Cancer Institute National Institutes of Health Bethesda MD USA;

Norwegian Radium Hospital Oslo Norway;

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1. Clinical evidence of a graft-versus-lymphoma effect against relapsed diffuse large B-cell lymphoma after allogeneic hematopoietic stem-cell transplantation. [J] . Bishop MR, Dean RM, Steinberg SM, Annals of oncology: official journal of the European Society for Medical Oncology . 2008,第11期

机译：异体造血干细胞移植后复发性弥漫性大B细胞淋巴瘤的移植物抗淋巴瘤作用的临床证据。
2. Long-Term Follow-up of Allogeneic Hematopoietic Stem Cell Transplantation for Follicular Lymphoma and Clinical Evidence of Graft-Versus-Lymphoma Effect in Post-Transplant Relapsed Patients [J] . Kohashi Sumiko, Mori Takehiko, Kato Jun, Biology of blood and marrow transplantation: journal of the American Society for Blood and Marrow Transplantation . 2016,第3Suppla1期

机译：异基因造血干细胞移植治疗滤泡性淋巴瘤的长期随访及移植后复发患者移植物抗淋巴瘤的临床证据
3. Allogeneic stem-cell transplantation as salvage therapy for patients with diffuse large B-cell non-Hodgkin's lymphoma relapsing after an autologous stem-cell transplantation: an analysis of the European Group for Blood and Marrow Transplantation Registry. [J] . van Kampen RJ, Canals C, Schouten HC, Journal of Clinical Oncology . 2011,第10期

机译：自体干细胞移植后同种异体干细胞移植作为弥漫性大B细胞非霍奇金淋巴瘤复发的抢救疗法：欧洲血液和骨髓移植注册组织分析。
4. Mutational profile of Diffuse Large B-cell Lymphoma with central nervous system relapse: analysis of CBioPortal for Cancer Genomics database [C] . Elena Voropaeva, Olga Beresina, Tatyana Pospelova, Conference on Cognitive Sciences, Genomics and Bioinformatics . 2020

机译：弥漫性大B细胞淋巴瘤与中枢神经系统复发的突变特征：用于癌症基因组学数据库的CBioPortal分析
5. Safety and Efficacy of the Immunomodulatory Drug (IMiD) Lenalidomide in Patients with Lymphoma: Development of RU051417I - Phase I/II Open-Label Study of R-ICE (Rituximab-Ifosfamide-Carboplatin-Etoposide) with Lenalidomide [R2-ICE] in Patients with First-Relapse/Primary Refractory Diffuse Large B-Cell Lymphoma (DLBCL). [D] . Kasi, Pashtoon Murtaza. 2018

机译：免疫调节药物来那度胺在淋巴瘤患者中的安全性和有效性：RU051417I-R-ICE（利妥昔单抗-异环磷酰胺-卡铂-依托泊苷）与来那度胺[R2-ICE]的I / II期开放标签研究的进展初次复发/原发性难治性弥漫性大B细胞淋巴瘤（DLBCL）。
6. Clinical evidence of a graft-versus-lymphoma effect against relapsed diffuse large B-cell lymphoma after allogeneic hematopoietic stem-cell transplantation [O] . M. R. Bishop, R. M. Dean, S. M. Steinberg, -1

机译：异基因造血干细胞移植后移植物抗淋巴瘤对复发性弥漫性大B细胞淋巴瘤的临床证据
7. Clinical evidence of a graft-versus-lymphoma effect against relapsed diffuse large B-cell lymphoma after allogeneic hematopoietic stem-cell transplantation [O] . Bishop, M. R., Dean, R. M., Steinberg, S. M., 2008

机译：异基因造血干细胞移植后移植物抗淋巴瘤对复发性弥漫性大B细胞淋巴瘤的临床证据

Clinical evidence of a graft-versus-lymphoma effect against relapsed diffuse large B-cell lymphoma after allogeneic hematopoietic stem-cell transplantation

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