A phase I–II study of everolimus (RAD001) in combination with imatinib in patients with imatinib-resistant gastrointestinaln         stromal tumors

G. D. Demetri

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A phase I–II study of everolimus (RAD001) in combination with imatinib in patients with imatinib-resistant gastrointestinaln stromal tumors

机译：依维莫司（RAD001）联合伊马替尼治疗伊马替尼耐药胃肠道间质瘤患者的I–II期研究

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Background: Imatinib is standard therapy for advanced gastrointestinal stromal tumors (GIST), but most patients develop resistance. This phase I–II study assessed the safety and efficacy of coadministering everolimus with imatinib in imatinib-resistant GIST.

机译：背景：伊马替尼是晚期胃肠道间质瘤（GIST）的标准疗法，但大多数患者会产生耐药性。这项I–II期研究评估了依维莫司与伊马替尼共同治疗对伊马替尼耐药的GIST的安全性和有效性。

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《Annals of Oncology》 |2010年第10期|p.1990-1998|共9页
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G. D. Demetri;
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1. A phase I-II study of everolimus (RAD001) in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors. [J] . Schoffski P, Reichardt P, Blay JY, Annals of oncology: official journal of the European Society for Medical Oncology . 2010,第10期

机译：依维莫司（RAD001）与伊马替尼联合用于伊马替尼耐药胃肠道间质瘤患者的I-II期研究。
2. Phase IV Study of Sunitinib in Chinese Patients with Imatinib-Resistant or Imatinib-Intolerant Gastrointestinal Stromal Tumors [J] . Lin Shen, Yan Sun, Jian-Ming Xu, Oncology and Therapy . 2017,第2期

机译：舒尼替尼在中国伊马替尼耐药或伊马替尼不耐受胃肠道间质瘤患者的IV期研究
3. Phase i study of sorafenib in combination with everolimus (RAD001) in patients with advanced neuroendocrine tumors [J] . ChanJ.A., MayerR.J., JacksonN., Cancer chemotherapy and pharmacology. . 2013,第5期

机译：索拉非尼联合依维莫司（RAD001）在晚期神经内分泌肿瘤患者中的一期研究
4. International classifications of gastrointestinal stromal tumor: a clue for adjuvant imatinib treatment [C] . Tzen Chin-Yuan International Gastric Cancer Congress . 2011

机译：胃肠道间质瘤的国际分类：佐剂伊马替尼治疗的线索
5. Molecular mechanisms of response in gastrointestinal stromal tumors treated with imatinib mesylate [D] . McAuliffe, John Christopher 2007

机译：甲磺酸伊马替尼治疗胃肠道间质瘤的分子机制
6. A Phase I Study of Single-Agent Nilotinib (AMN107) or in Combination with Imatinib in Patients with Imatinib-Resistant Gastrointestinal Stromal Tumors [O] . George D Demetri, Paolo G Casali, Jean-Yves Blay, -1

机译：I阶段研究单孕尼洛替尼（AMN107）或与伊马替尼抗性胃肠道间质瘤患者组合的伊马替尼
7. Phase I/II Study of Trastuzumab in Combination With Everolimus (RAD001) in Patients With HER2-Overexpressing Metastatic Breast Cancer Who Progressed on Trastuzumab-Based Therapy [O] . Phuong K. Morrow, Gerburg M. Wulf, Joe Ensor, 2011

机译：曲妥珠单抗与血尿症（RAD001）组合的血管血清（RAD001）研究患有曲妥珠菇的疗效乳腺癌患者患者

A phase I–II study of everolimus (RAD001) in combination with imatinib in patients with imatinib-resistant gastrointestinaln stromal tumors

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