Effect of intracerebroventricular injections of prolactin-releasing peptide on prolactin release and stress-related responses in steers

摘要

Some evidence suggests that there might be a species difference in the effect of intracerebroventricularly administered (ICV) prolactin-releasing peptide (PrRP) between rodents and sheep. We compared the levels of cortisol (CORT) and prolactin (PRL), rectal temperature (RT) and behavioral responses to ICV bovine PrRP (bPrRP) in steers. ICV bPrRP (0.2, 2 and 20?nmol/200?μL) tended to evoke a dose-related increase in CORT concentrations and 0.2?nmol of bPrRP induced transient increase in PRL concentrations. A significant time–treatment interaction was observed for the percent change of CORT (P?