Noninvasive Imaging of Dendrimer-Type N-Glycan Clusters: In Vivo Dynamics Dependence on Oligosaccharide Structure†

著录项

• 来源
  《Angewandte Chemie International Edition》 |2010年第44期|p.8195-8200|共6页
• 作者

  Dr. Katsunori Tanaka; Dr. Eric R. O. Siwu; Kaori Minami; Dr. Koki Hasegawa; Dr. Satoshi Nozaki; Dr. Yousuke Kanayama; Koichi Koyama; Dr. Weihsu C. Chen; Prof. James C. Paulson; Prof.#x2005; Dr. Yasuyoshi Watanabe; Prof.#x2005; Dr. Koichi Fukase;

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• 作者单位

  Department of Chemistry, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka-shi, Osaka 560-0043 (Japan), Fax: (+81) 6-6850-5419 http://www.chem.sci.osaka-u.ac.jp/lab/fukase/;

  |Department of Chemistry, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka-shi, Osaka 560-0043 (Japan), Fax: (+81) 6-6850-5419 http://www.chem.sci.osaka-u.ac.jp/lab/fukase/;

  |Department of Chemistry, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka-shi, Osaka 560-0043 (Japan), Fax: (+81) 6-6850-5419 http://www.chem.sci.osaka-u.ac.jp/lab/fukase/;

  RIKEN Center for Molecular Imaging Science, 6-7-3 Minatojima, Chuo-ku, Kobe-shi, Hyogo 650-0047 (Japan);

  RIKEN Center for Molecular Imaging Science, 6-7-3 Minatojima, Chuo-ku, Kobe-shi, Hyogo 650-0047 (Japan);

  RIKEN Center for Molecular Imaging Science, 6-7-3 Minatojima, Chuo-ku, Kobe-shi, Hyogo 650-0047 (Japan);

  Kishida Chemical Co., Ltd. 14-10 Technopark, Sanda-shi, Hyogo 669-1339 (Japan);

  Department of Chemical Physiology, Joint Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, MEM-L71, La Jolla, CA 92037 (USA);

  Department of Chemical Physiology, Joint Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, MEM-L71, La Jolla, CA 92037 (USA);

  RIKEN Center for Molecular Imaging Science, 6-7-3 Minatojima, Chuo-ku, Kobe-shi, Hyogo 650-0047 (Japan);

  Department of Chemistry, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka-shi, Osaka 560-0043 (Japan), Fax: (+81) 6-6850-5419 http://www.chem.sci.osaka-u.ac.jp/lab/fukase/;

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• 关键词

  antitumor agents; dendrimers; fluorescent probes; oligosaccharides; positron emission tomography;

  机译：抗肿瘤剂;树状大分子;荧光探针;低聚糖;正电子发射断层显像;