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The application of digital pulse amplitude tonometry to the diagnostic investigation of endothelial dysfunction in men with erectile dysfunction

机译:数字脉冲幅度眼压计在勃起功能障碍男性血管内皮功能障碍诊断研究中的应用

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The application of digital pulse amplitude by fingertip peripheral arterial tonometry (PAT) device in patients with erectile dysfunction (ED) has never been performed. We investigated the diagnostic value of reactive hyperaemia (RH) and augmentation index (AI) as evaluated using PAT in men with ED of any origin. A total of 40 patients underwent diagnostic investigation for ED, including dynamic penile duplex ultrasound (PDU) and PAT device. Moreover, 30 patients without ED served as controls. According to PDU cutoff at 35?cm/sec, patients were divided into vascular (n?=?30) and nonvascular (n?=?10) ED aetiology. Moreover, controls with (n?=?10) or without (n?=?20) vascular risk factors (VRFs) were studied in a separate analysis. Average RH-PAT was not different in men with or without ED (P?=?0.56) independently of VRFs. The AI was higher in men with ED compared with the controls (P?
机译:从未通过指尖外周动脉眼压计(PAT)装置在勃起功能障碍(ED)患者中应用数字脉冲幅度。我们调查了使用PAT对任何来源的ED男性的反应性充血(RH)和增强指数(AI)的诊断价值。总共40例患者接受了ED的诊断研究,包括动态阴茎双工超声(PDU)和PAT装置。此外,将30例无ED的患者作为对照。根据35厘米/秒的PDU截断率,将患者分为血管性ED病因(n≥30)和非血管性ED(n≥10)。此外,在单独的分析中研究了具有(n≥10)或不具有(n≥20)血管危险因子(VRF)的对照。有或没有ED的男性的平均RH-PAT没有差异(P≥0.56),与VRF无关。与对照组相比,ED男性的AI更高(P 0.0001),并且在控制是否存在VRF时(P 0.0001)。还发现AI与PSV之间存在反比关系(r 2 α=Δ0.72,Pα<Δ0.0001)。总而言之,独立于VRFs的血管性ED男性中AI升高但RH-PAT并未受损,这可能是早期检测到血管损害的早期检测结果,而血管损害可能在发展为血管性ED的低风险人群中出现。

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