Reply: The Respiratory Extracorporeal Membrane Oxygenation Survival Prediction Score: Several Potential Roles in Our Bedside Practice in Intensive Care

摘要

We thank Dr. Mourad Senussi for his interest in the Respiratory Extracorporeal Membrane Oxygenation (ECMO) Survival Prediction (RESP) score. We agree that the RESP score has been developed on patients already receiving ECMO and has not been validated for the prediction of survival in a more general population of patients with severe acute respiratory failure in whom ECMO has not yet been instituted. However, to the best of our knowledge, a large international database that includes patients with severe acute respiratory failure who are potential candidates for ECMO rescue therapy, and that indicates those treated with and without ECMO, does not actually exist. Such a cohort might also be subject to bias because patients of equal severity of illness may not receive ECMO either because they are not considered "severe enough" for ECMO or are considered too sick for "futile ECMO."