Cerebral metabolism in sleep apnea: evaluation by magnetic resonance spectroscopy

摘要

Repeated apneic episodes during sleep may lead to cerebral damage in patients with obstructive sleep apnea (OSA). We performed proton magnetic resonance (MR) spectroscopic studies to exam- ine cerebral metabolism in patients with OSA. We studied 15 healthy subjects and 23 patients with OSA who displayed no anatomical abnormalities on MR imaging. The patients were classified into Two groups based on the results of polysomnography: mild OSA (11 patients) or moderate to severe OSA (12 patients).