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首页> 外文期刊>Alcohol and Alcoholism >Low-Alcohol Beers: Contribution to Blood-Ethanol Concentration and Its Elevation above the UK Legal Limit after ‘Topping-up’
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Low-Alcohol Beers: Contribution to Blood-Ethanol Concentration and Its Elevation above the UK Legal Limit after ‘Topping-up’

机译:低酒精啤酒:“补足”后对血液乙醇浓度的贡献及其升高超过英国法律限制

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Aims: The aim of this study was to establish the contribution of low-alcohol beers to blood-ethanol concentration (BEC) and to test if ‘topping-up’ with these beverages can increase BEC above the 80 mg/dl UK legal limit. Methods: Healthy male and female volunteers received a dose of ethanol designed to give a BEC of just below 80 mg/dl, and then received one pint (600 ml) of a 1% v/v alcohol beer in the fasting state or after lunch, or of a zero-alcohol or a 0.5% v/v alcohol beer after fasting. BEC was determined enzymatically and data were subjected to ANOVA. Results: Topping-up with a pint of a 1% v/v alcohol beer increased BEC 80 mg/dl in fasting subjects, contributing an extra 12–17 mg/dl, which lasted longer in males (80 min) than in females (20 min). A 0.5% v/v alcohol beer increased BEC above 80 mg/dl only in males, which lasted for 60 min. After food intake, the 1% v/v alcohol beer increased BEC above 80 mg/dl transiently only in males. Conclusions: Low-alcohol beers make a significant contribution to blood-ethanol concentration and can increase it above the UK legal limit. Their use as a ‘top-up’ should be discouraged. Low-alcohol beers have a place as a substitute for normal-strength beverages as a strategy for decreasing alcohol consumption in general and in countries where low legal alcohol limits are in force or being contemplated.
机译:目的:这项研究的目的是确定低度啤酒对血液乙醇浓度(BEC)的贡献,并测试这些饮料的“增补”是否可以使BEC升高到英国法律规定的80 mg / dl以上。方法:健康的男性和女性志愿者接受的乙醇设计可使BEC低于80 mg / dl,然后在空腹状态或午餐后接受一品脱(600 ml)的1%v / v酒精啤酒,或禁食后的零酒精或0.5%v / v酒精啤酒。酶法测定BEC,并对数据进行方差分析。结果:在一品脱的1%v / v酒精啤酒中补充,在禁食的受试者中BEC大于80 mg / dl,增加了12–17 mg / dl,男性(80分钟)的持续时间比女性更长(20分钟)。 0.5%v / v的酒精啤酒仅在男性中将BEC升高到80 mg / dl以上,持续60分钟。进食后,仅男性中的1%v / v酒精啤酒会暂时使BEC升高至80 mg / dl以上。结论:低酒精啤酒对血液中的乙醇浓度有重大贡献,并且可以使血液中的乙醇浓度超过英国的法定限值。不应将其用作“充值”。低酒精啤酒可以代替普通强度的饮料,作为降低酒精消费的策略,在一般情况下以及在法定低酒精浓度强制实施或正在考虑的国家中,低酒精啤酒都可以作为降低酒精消耗的策略。

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  • 来源
    《Alcohol and Alcoholism》 |2009年第4期|p.403-408|共6页
  • 作者单位

    1The Cardiff School of Health Sciences, University of Wales Institute, Cardiff, UK 2Department of Medical Biochemistry, University Hospital of Wales, Cardiff, UK 3South Wales Forensic Psychiatric Service, The Caswell Clinic, Bridgend, UK;

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