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Advanced Functional Structure-Based Sensing and Imaging Strategies for Cancer Detection: Possibilities, Opportunities, Challenges, and Prospects

机译:用于癌症检测的基于功能结构的先进传感和成像策略:可能性,机遇,挑战和前景

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摘要

Cancer is the second most common cause of death in the world. The principal limitations thus far encountered in the clinical practice of probing cancer are diverse and include low sensitivity, time consumption, bulkiness, and cost. In this respect, nanomaterial (NM)-based sensing techniques are recognized as a superior alternative to efficiently resolve such limitations. A better understanding of NM-based sensing platforms is thus important so that these novel avenues can easily be explored for clinical applications. These platforms have the merits of high sensitivity, high specificity, rapid response, and easy-to-read signals. This review offers a comprehensive survey of NM-based advanced cancer-sensing techniques and will help the scientific community establish optimum sensing strategies based on an accurate assessment of the interactions between cancer biomarkers and NM-based platforms.
机译:癌症是世界上第二大最常见的死亡原因。迄今为止,在探索癌症的临床实践中遇到的主要限制是多种多样的,并且包括低灵敏度,时间消耗,体积大和成本低。在这方面,基于纳米材料(NM)的传感技术被认为是有效解决此类局限性的一种高级选择。因此,更好地理解基于NM的传感平台非常重要,以便可以轻松地探索这些新颖的途径以用于临床应用。这些平台具有高灵敏度,高特异性,快速响应和易于读取的信号的优点。这篇综述提供了对基于NM的先进癌症传感技术的全面调查,并将基于对癌症生物标记物与基于NM的平台之间相互作用的准确评估,帮助科学界建立最佳的传感策略。

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