EFFECTS OF SUCROSE/NaCl MIXTURES STIMULATION ON C-FOS-LIKE IMMUNOREACTIVITY IN THE TASTE-RELATED NUCLEI IN RATS

摘要

Objective To investigate the changes of neuronal activation in taste-related nuclei following intraoral taste stimulation with binary taste mixtures of sucrose and NaCl. Methods Neuronal activation in response to intraoral taste stimulation with 0. 5 mol · L~(-1) sucrose, 0. 3 mol · L~(-1) NaCl, sucrose+NaCl mixture and distilled water was e-valuated in taste-related nuclei by using c-Fos-like immunoreactivity(c-FLI) in the rats deprived of water overnight. Results The consumption of sucrose + NaCl mixture was lower than that of sucrose solution. Intraoral sucrose or NaCl stimulation induced more c-FLI than distilled water in the external lateral subnucleus of the rostral parabrachial nucleus (PBN), but the c-FLI induced by intraoral sucrose+NaCl mixture stimulation was less than that induced by sucrose solution in this subnucleus. Compared with distilled water, the intraoral sucrose or sucrose+NaCl mixture stimulation induced more c-FLI in the central amygdala. Conclusion These results suggest that salty taste has a suppressive effect on the neuronal activations induced by sweet taste in the external lateral subnucleus of rostral PBN in rats.