Clopidogrel Use Is Associated With an Increased Prevalence of Cerebral Microbleeds in a Stroke‐Free Population: The Rotterdam Study

摘要

BackgroundAlthough clopidogrel reduces the incidence of atherothrombotic events, its use is associated with an increased risk of major bleeding. Cerebral microbleeds (CMBs) are indicative of subclinical microangiopathy in the brain and may prelude symptomatic intracerebral hemorrhage. We examined the association between use of clopidogrel and CMBs in persons without a history of stroke.