Dietary Mannan Oligosaccharides Modulate Gut Microbiota Increase Fecal Bile Acid Excretion and Decrease Plasma Cholesterol and Atherosclerosis Development

摘要

ScopeMannan oligosaccharides (MOS) have proven effective at improving growth performance, while also reducing hyperlipidemia and inflammation. As atherosclerosis is accelerated both by hyperlipidemia and inflammation, we aim to determine the effect of dietary MOS on atherosclerosis development in hyperlipidemic ApoE*3‐Leiden.CETP (E3L.CETP) mice, a well‐established model for human‐like lipoprotein metabolism.